文献类型： 外文期刊
作者： Jun, Liu Wu 1 ; Yi, Fang 1 ; Shao Yong-gang 1 ; Xin, Fang Guang 2 ; Chuan, Tian Ke 6 ; Xia, Huang Xi 1 ; Hong, Chen 4 ; Q 1 ;
作者机构： 1.Xinjiang Agr Univ, Coll Anim Sci, Urumqi 830052, Xinjiang, Peoples R China
2.Anim Husb Bur, Foreign Funds Project Off, Urumqi 830001, Xinjiang, Peoples R China
3.Goat Res Ctr Aksu Prefecture, Aksu City 843000, Xinjiang, Peoples R China
4.NW A&F Univ, Coll Anim Sci & Technol, Shaanxi Key Lab Mol Biol Agr, Yangling 712100, Shaanxi, Peoples R China
5.Xuzhou Normal Univ, Inst Cellular & Mol Biol, Xuzhou 221116, Jiangsu, Peoples R China
6.Xinjiang Acad Anim Sci, Urumqi 830000, Xinjiang, Peoples R China
关键词： Cashmere goat;cashmere traits;breed;KAP16.5 gene;deletion mutation
期刊名称：ASIAN JOURNAL OF ANIMAL AND VETERINARY ADVANCES （ 影响因子：0.869； ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： In this study, a novel deletion mutation in the whole CDS region at cashmere goat KAP16.5 gene locus is reported, which result showed the deletion of KAP16.5 gene in 816 cashmere goat samples was firstly detected in China. At the same time, parts of these samples sequenced. However, there are not many studies of goat KAP16.5 gene and its polymorphisms in literary sources. The polymorphism was studied in three Xinjiang local goat breeds of China. The results showed that there was 15 bp-deletion mutation in this gene. The frequencies of the KAP16.5-Y allele in Xinjiang goat (n = 220), Nanjiang cashmere goat (n = 310) and BoGeDa cashmere goat breeds (n = 286) were 0.9591, 0.8694 and 0.8846, respectively. The X~2 showed that the genotype distributions in these three cashmere goat breeds were not in agreement with Hardy-Weinberg equilibrium. According to the classification of PIC, Nanjiang cashmere goat was more polymorphic at this locus. Moreover, the 15 bp-deletion mutation was described at KAP16.5 locus for the first time and not have described at KAP16.5 locus. Then, the deletion polymorphisms within the KAP16.5 have been associated with economic production traits data in Nanjiang cashmere goat breed shown no significant (p>0.05).
- 相关文献
