Identification of SNPs and expression patterns of ALB, AHSG and GC genes and their association with growth traits in Hu sheep
文献类型： 外文期刊
作者： Zhao, Liming 1 ; Wang, Weimin 1 ; Wang, Xiaojuan 1 ; Zhang, Deyin 4 ; Li, Xiaolong 1 ; Zhao, Yuan 1 ; Zhang, Yukun 1 ; Xu, Dan 1 ; Cheng, Jiangbo 1 ; Wang, Jianghui 1 ; Li, Wenxin 1 ; Lin, Changchun 1 ; Wu, Weiwei 3 ; Zhang, Xiaoxue 1 ; Zheng, Wenxin 2 ;
作者机构： 1.Gansu Agr Univ, Coll Anim Sci & Technol, Lanzhou 730070, Gansu, Peoples R China
2.Xinjiang Acad Anim Sci, Inst Anim Husb Qual Stand, Urumqi 830000, Xinjiang, Peoples R China
3.Xinjiang Acad Anim Sci, Inst Anim Sci, Urumqi 830000, Xinjiang, Peoples R China
4.Lanzhou Univ, Coll Pastoral Agr Sci & Technol, State Key Lab Grassland Agroecosystems, Lanzhou 730020, Gansu, Peoples R China
关键词： Hu sheep; ALB; AHSG; GC; Growth traits; Association; SNP; qRT-PCR
期刊名称：GENE （ 影响因子：3.5； 五年影响因子：3.3 ）
ISSN： 0378-1119
年卷期： 2023 年 853 卷
页码：
收录情况： SCI
摘要： Growth traits are economically important traits in sheep breeding. This study was conducted to evaluate the polymorphisms of ALB, AHSG and GC genes and their association with growth traits in Hu sheep. We measured and recorded the body weight (BW), body height (BH), body length (BL) and feed conversion ratio (FCR) of 1418 male Hu sheep raised in the same environment from 80 to 180 days of age. The total of four SNPs in the ALB, AHSG and GC genes were identified by direct sequencing technology. The results of association analysis showed that two loci (g.8699 A>T and g.13458 T>C) of ALB gene significantly affect average daily gain (ADG; P < 0.05). The genotypes of SNP g.2454 T>C in AHSG gene were significantly associated with ADG and FCR (P < 0.05). There were significant associations between GC g.19484 A>C and BW, BH and BL (P < 0.05). The results of qRTPCR showed that ALB, AHSG, and GC genes were extremely significantly higher in H_BW sheep compared with those in the L_BW sheep (P < 0.01). These results revealed that ALB-1 g.8699 A>T, ALB-2 g.13458 T>C, AHSG g.2454 T>C and GC g.19484 A>C loci are potential molecular markers for Hu sheep breeding.
- 相关文献
作者其他论文 更多>>
-
Two mutations at KRT74 and EDAR synergistically drive the fine-wool production in Chinese sheep
作者：Liang, Benmeng;Bai, Tianyou;Zhao, Yuhetian;Han, Jiangang;He, Xiaohong;Pu, Yabin;Ma, Yuehui;Jiang, Lin;Liang, Benmeng;Liu, Jianfeng;Liang, Benmeng;Liu, Jianfeng;Liang, Benmeng;Bai, Tianyou;Zhao, Yuhetian;Han, Jiangang;He, Xiaohong;Pu, Yabin;Ma, Yuehui;Jiang, Lin;Han, Jiangang;Wang, Chunxin;Liu, Wujun;Ma, Qing;Tian, Kechuan;Tian, Kechuan;Zheng, Wenxin;Liu, Nan
关键词：Chinese fine wool sheep; Whole genome sequencing; Genomic selection signature; Follicle density; Missense; Regulatory
-
Analysis of the Genetic Relationship and Inbreeding Coefficient of the Hetian Qing Donkey through a Simplified Genome Sequencing Technology
作者：Liu, Bo;Gong, Shujuan;Liu, Bo;Tulafu, Hanikezi;Tao, Weikun;Wu, Weiwei;Zhang, Rongyin;Adili, Abulikemu;Liu, Li;Huang, Juncheng
关键词：Hetian Qing donkey; simplified genome; genetic diversity; population structure
-
Development of a Device and Algorithm Research for Akhal-Teke Activity Level Analysis
作者：Chen, Xuan;Li, Fuzhong;Fan, Qijie;Chen, Xuan;Li, Jinxing;Fan, Qijie;Guo, Leifeng;Li, Jinxing;Kwan, Paul;Zheng, Wenxin
关键词：activity level classification; horse; sensors; threshold analysis
-
Identification of AGO2 and PLEC genes polymorphisms in Hu sheep and their relationship with body size traits
作者：Liu, Jia;Yang, Xiaobin;Huang, Yongliang;Cui, Panpan;Ma, Zongwu;Zeng, Xiwen;Zhai, Rui;Zhang, Xiaoxue;Zheng, Wenxin;Wang, Weimin;Weng, Xiuxiu;Wu, Weiwei
关键词：Hu sheep; AGO2; pLEC; body size traits; qRT-PCR
-
CircERCC6 Positively Regulates the Induced Activation of SHF Stem Cells in Cashmere Goats via the miR-412-3p/BNC2 Axis in an m6A-Dependent Manner
作者：Zhang, Qi;Fan, Yixing;Bai, Man;Zhu, Yubo;Wang, Zeying;Shen, Jincheng;Xu, Ruqing;Bai, Wenlin;Zheng, Wenxin;Zheng, Wenxin
关键词：CircERCC6; N-6-Methyladenosine; SHF stem cells; induced activation; cashmere goats
-
Polymorphisms of PLIN1 and MOGAT1 genes and their association with feed efficiency in Hu sheep
作者：Ma, Zongwu;Xu, Dan;Yang, Xiaobin;Liu, Jia;He, Lijuan;Chen, Zhanyu;Gong, Ping;Zhang, Xiaoxue;Gong, Ping;Wang, Weimin;Zhang, Deyin;Zhang, Yukun;Zhao, Yuan;Li, Xiaolong;Zhao, Liming;Cheng, Jiangbo
关键词：Feed efficiency; PLIN1; MOGAT1; Single nucleotide polymorphisms; Hu sheep
-
Identification of the FGB gene polymorphism and analysis of its association with fat deposition traits in Hu sheep
作者：He, Lijuan;Wang, Xiaojuan;Xu, Dan;Ma, Zongwu;Yang, Xiaobin;Huang, Zhiqiang;Cai, Youxin;Liu, Xiaoqiang;Chen, Zhanyu;Zhang, Xiaoxue;Wang, Weimin;Zhang, Deyin;Zhang, Yukun;Zhao, Yuan;Zhao, Liming;Li, Xiaolong;Cheng, Jiangbo;Weng, Xiuxiu;Lin, Changchun;Gong, Ping
关键词：Association analysis; Hu sheep; single nucleotide polymorphism; fat deposition; FGB gene
