Recombinant pseudorabies virus expressing P12A and 3C of FMDV can partially protect piglets against FMDV challenge

Zhang, Keshan; Wang, Qingang; He, Yannan; Xu, Zhuofei; Xiang, Min; Wu, Bin; Chen, Huanchun; Zhang, Keshan; Huang, Jiong; SCI

机构： Huazhong Agr Univ, Coll Vet Med, State Key Lab Agr Microbiol, Wuhan 430070, Hubei, Peoples R China; Chinese Acad Agr Sci, Minist Agr, Lanzhou Vet Res Inst,Key Lab Anim Virol, State Key Lab Vet Etiol Biol,Natl Foot & Mouth Di, Lanzhou 730046, Gansu, Peoples R China; Xinjiang Acad Anim Sci, Inst Vet Med, Urumqi 830000, Peoples R China;

关键词： 3C protease: expression EC 3.4.22.28 capsid precursor polypeptide: P12A expression PRV-P12A3C: immunologic-drug immunostimulant-drug efficacy disease severity humoral immune response cellular immune response P12A3C immunogenicity