您好，欢迎访问新疆畜牧科学院 机构知识库！

Study on the region-specific expression of epididymis mRNA in the rams

文献类型： 外文期刊

作者： Wu, Cuiling 1 ; Wang, Chunxin 2 ; Zhai, Bo 2 ; Zhao, Yunhui 2 ; Zhao, Zhuo 2 ; Yuan, Zhiyu 2 ; Fu, Xuefeng 3 ; Zhang, Min 1 ;

作者机构： 1.Xinjiang Agr Univ, Coll Anim Sci, Urumqi, Peoples R China

2.Jilin Acad Agr Sci, Branch Anim Husb, Gongzhuling, Peoples R China

3.Xinjiang Acad Anim Sci, Inst Anim Sci, Key Lab Genet Breeding & Reprod Xinjiang Wool She, Urumqi, Peoples R China

期刊名称：PLOS ONE （ 影响因子：3.24； 五年影响因子：3.788 ）

ISSN： 1932-6203

年卷期： 2021 年 16 卷 1 期

页码：

收录情况： SCI

摘要： The epididymis is divided into three regions including the caput, corpus and cauda. Gene expression profiles in different regions indicate the different functions of epididymis which are crucial for sperm maturation. In this study, three one-year-old rams was used as the experimental animal. Transcriptome sequencing technology was used to sequence mRNA in the caput, corpus and cauda of the epididymis. Based on the spatiotemporal-specific expression pattern in the epididymis, the mRNA expression profiles of the three parts of the epididymis were analysed. Region-specifically expressed genes were analysed by GO and KEGG analyses to screen the key genes involved in sheep sperm maturation. We obtained 129, 54 and 99 specifically expressed genes in the caput, corpus and cauda, respectively. And twenty specific expressed genes related to sperm maturation were used to construct functional networks. The heatmap showed that 6 genes of LCN protein family were highly expressed in the head of epididymis of sheep. We infer that sperm maturation is gradual in the epididymis and that there are significant differences in epididymal gene expression patterns between different species. This provides a data resource for analysing the regulatory mechanism of epididymis genes related to sperm maturation in rams.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：新疆畜牧科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台