文献类型： 外文期刊
作者： Zhang, WB 1 ; Li, J 2 ; McManus, DP 3 ;
作者机构： 1.Queensland Inst Med Res, Mol Parasitol Lab, Australian Ctr Int & Trop Hlth & Nutr, Brisbane, Qld 4029, Australia
2.Univ Queensland, Brisbane, Qld 4029, Australia
3.Xinjiang Acad Anim Sci, Vet Res Inst, Urumqi 830000, Xinjiang, Peoples R China
期刊名称：CLINICAL MICROBIOLOGY REVIEWS （ 影响因子：26.132； 五年影响因子：32.976 ）
ISSN： 0893-8512
年卷期： 2003 年 16 卷 1 期
页码：
收录情况： SCI
摘要： Echinococcosis is a cosmopolitan zoonosis caused by adult or larval stages of cestodes belonging to the genus Echinococcus (family Taeniidae). The two major species of medical and public health importance are Echinococcus granulosus and E. multilocularis, which cause cystic echinococcosis (CE) and alveolar echinococcosis (AE), respectively. Both CE and AE are both serious diseases, the latter especially so, with a high fatality rate and poor prognosis if managed inappropriately. This review discusses new concepts and approaches in the immunology and diagnosis of CE, but comparative reference has also been made to AE infection and to earlier pivotal studies of both diseases. The review considers immunity to infection in the intermediate and definitive hosts, innate resistance, evasion of the immune system, and vaccination of intermediate and definitive hosts, and it particularly emphasizes procedures for diagnosis of CE and AE, including the value of immunodiagnostic approaches. There is also discussion of the new advances in recombinant and related DNA technologies, especially application of PCR, that are providing powerful tools in the fields of vaccinology and molecular diagnosis of echinococcosis.
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Immunoglobulin profiles in a murine intermediate host model of resistance for Echinococcus granulosus infection
作者：Zhang, WB;You, H;Li, J;Zhang, ZZ;Turson, G;Aili, H;Wang, JC;McManus, DP
关键词：Echinococcus granulosus;murine model of resistance;oncospheres;primary infection;secondary infection;immunoglobulin profiles;antibodies;Antigen B
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Further studies on an intermediate host murine model showing that a primary Echinococcus granulosus infection is protective against subsequent oncospheral challenge
作者：Zhang, WB;You, H;Zhang, ZZ;Turson, G;Hasyet, A;McManus, DP
关键词：Echinococcus granulosus;hydatid disease;oncospheres;hydatid cysts;murine host;protection
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ECHINOCOCCOSIS
作者：McManus, DP;Zhang, WB;Li, J;Bartley, PB
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