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Whole-genome sequencing of 128 camels across Asia reveals origin and migration of domestic Bactrian camels

文献类型: 外文期刊

作者: Ming, Liang 1 ; Yuan, Liyun 3 ; Yi, Li 1 ; Ding, Guohui 3 ; Hasi, Surong 6 ; Chen, Gangliang 7 ; Jambl, Tuyatsetseg 8 ; H 1 ;

作者机构: 1.Inner Mongolia Agr Univ, Coll Food Sci & Engn, Key Lab Dairy Biotechnol & Engn, Minist Educ, Hohhot, Peoples R China

2.Inner Mongolia Inst Camel Res, Hohhot, Peoples R China

3.Chinese Acad Sci, Key Lab Computat Biol, Shanghai Inst Nutr & Hlth, CAS MPG Partner Inst Computat Biol,Shanghai Inst, Shanghai, Peoples R China

4.Chinese Acad Sci, Shanghai Inst Nutr & Hlth, CAS MPG Partner Inst Computat Biol, Biomed Big Data Ctr,Shanghai Inst Biol Sci, Shanghai, Peoples R China

5.Chinese Acad Sci, Shanghai Inst Biol Sci, Guian Biomed Big Data Ctr, Guiyang, Guizhou, Peoples R China

6.Inner Mongolia Agr Univ, Coll Vet Med, Key Lab Clin Diag & Treatment Technol Anim Dis, Minist Agr, Hohhot, Peoples R China

7.Xingjiang Wangyuan Camel Milk Ltd Co, Bactrian Camel Acad Altai, Xijiang, Fuhai County, Peoples R China

8.Mongolian Univ Sci & Technol, Coll Ind Technol, Ulaanbaater, Mongolia

9.Univ Mohaghegh Arabili, Ardebil, Iran

10.China Mongolia Joint Lab Biomacromol Res, Ulaanbaatar, Mongolia

11.Minist Nat & Environm, Mongolian Wild Camel Protect Area, Ulaanbaatar, Mongolia

12.Nonpubl Joint Stock Co, Kirovski Plant, Ulaanbaatar, Republic Of Kal, Russia

13.Mongolian Acad Sci, Inst Chem & Chem Technol, Ulaanbaatar, Mongolia

14.Bactrian Camel Inst Alxa, Alxa, Inner Mongolia, Peoples R China

15.Xinjiang Acad Anim Sci, Anim Sci Inst, Urumqi, Peoples R China

16.Anim Husb Bur North Urad, Bayannuur, Inner Mongolia, Peoples R China

17.Anim Husb Workstat West Sunid, Xiliingol, Inner Mongolia, Peoples R China

18.Kalmyk State Univ, Agr Fac, Elista, Republic Of Kal, Russia

19.Kazakh Natl Agr Univ, Alma Ata, Kazakhstan

20.Inner Mongolia Agr Univ, Coll Anim Sci, Hohhot, Peoples R China

21.Inner Mongolia Med Univ, Dept Pharm, Affiliated Hosp, Hohhot, Peoples R China

22.Inst Technol, Ulaanbaatar, Mongolia

23.Shanghai Ind Technol Inst, Shanghai Ctr Bioinformat Technol, Shanghai, Peoples R China

24.Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Shanghai, Peoples R China

期刊名称:COMMUNICATIONS BIOLOGY ( 影响因子:6.268; 五年影响因子:6.268 )

ISSN:

年卷期: 2020 年 3 卷 1 期

页码:

收录情况: SCI

摘要: The domestic Bactrian camels were treated as one of the principal means of locomotion between the eastern and western cultures in history. However, whether they originated from East Asia or Central Asia remains elusive. To address this question, we perform whole-genome sequencing of 128 camels across Asia. The extant wild and domestic Bactrian camels show remarkable genetic divergence, as they were split from dromedaries. The wild Bactrian camels also contribute little to the ancestry of domestic ones, although they share close habitat in East Asia. Interestingly, among the domestic Bactrian camels, those from Iran exhibit the largest genetic distance and the earliest split from all others in the phylogeny, despite evident admixture between domestic Bactrian camels and dromedaries living in Central Asia. Taken together, our study support the Central Asian origin of domestic Bactrian camels, which were then immigrated eastward to Mongolia where native wild Bactrian camels inhabit. Ming, Yuan et al. performed whole-genome sequencing on 128 wild and domesticated Bactrian camels across Asia. They show that wild and domestic Bactrian camels are genetically diverged from dromedaries, and that wild camels contributed little to domestic camel ancestry despite sharing a habitat in East Asia.

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